| Description | 4-Hydroxypropranolol D7 hydrochloride is deuterium-labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26). |
| Synonyms | (±)-4-hydroxy Propranolol D7 hydrochloride, 4-Hydroxypropranolol D7 hydrochloride |
| molecular weight | 318.85 |
| Molecular formula | C16H22ClNO3 |
| CAS | 1219804-03-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Fitzgerald JD, et al. Pharmacology of 4-hydroxypropranolol, a metabolite of propranolol. Br J Pharmacol. 1971 Sep;43(1):222-35. 2. Nelson WL, et al. The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite. J Med Chem. 1984 Jul;27(7):857-61. 3. Ivan Tong Mak, et al. Potent Antioxidant Properties of 4-Hydroxyl-propranolol. Journal of Pharmacology and Experimental Therapeutics. 2004, 308(1):85-90. |