| Description | 4,7-DIHYDROXYCOUMARIN is a naturally occurring coumarin derivative found in a variety of plants, including parsley and chamomile. It has been found to inhibit the activity of several enzymes, including cytochrome P450, cyclooxygenase and lipoxygenase. It can also bind to DNA, regulate gene expression, and inhibit cell cycle progression. It can also induce apoptosis in tumor cells and reduce inflammation. |
| molecular weight | 178.14 |
| Molecular formula | C9H6O4 |
| CAS | 1983-81-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/mL (336.81 mM) |
| References | 1. Zhao, H., Neamati, N., Hong, H., Mazumder, A., Wang, S., & Sunder, S. et al. (1997). Coumarin-Based Inhibitors of HIV Integrase1. Journal Of Medicinal Chemistry, 40(2), 242-249. doi: 10.1021/jm960450v |