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3-Nitrocoumarin

CAS No.: 28448-04-6

3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.
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Description 3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.
Synonyms 3-nitrochromen-2-one
molecular weight 191.14
Molecular formula C9H5NO4
CAS 28448-04-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 90mg/mL (470.9mM)
References 1. Ward PD, et al. Phospholipase C-gamma modulates epithelial tight junction permeability through hyperphosphorylation of tight junction proteins. J Biol Chem. 2002 Sep 20;277(38):35760-5.