| Description | (2S,3R,4S)-4-Hydroxyisoleucine (Hydroxyisoleucine) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secretion from pancreatic cells. HIL activates insulin receptor substrate-associated phosphoinositide 3 (PI3) kinase activity. HIL reduces plasma levels of triglycerides, free fatty acids and cholesterol. |
| Synonyms | (4S)-4-Hydroxy-L-isoleucine, (4S)4-羟基异亮氨酸, Hydroxyisoleucine |
| molecular weight | 147.17 |
| Molecular formula | C6H13NO3 |
| CAS | 55399-93-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: < 1 mg/mL (insoluble) |