| Description | 2-Quinolinecarboxaldehyde (Quinoline-2-carbaldehyde) is a small rigid molecule that is a compound in the Henry reaction and subsequent elimination. 2-Quinolinecarboxaldehyde inhibits AChE with an IC50 of 13.48 μM. |
| Target activity | AChE:13.48 μM |
| Synonyms | Quinoline-2-carbaldehyde |
| molecular weight | 157.17 |
| Molecular formula | C10H7NO |
| CAS | 5470-96-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 50 mg/mL (318.13 mM) |
| References | 1. Küçük V, et al. Combined experimental and theoretical studies on the vibrational spectra of 2-quinolinecarboxaldehyde. Spectrochim Acta A Mol Biomol Spectrosc. 2012;85(1):92-98. 2. Timchenko YV, et al. A novel simple and sensitive approach for determination of 1,1-dimethylhydrazine in aqueous samples by high performance liquid chromatography with ultraviolet and tandem mass spectrometric detection after derivatization with unsubstituted aromatic aldehydes. Chemosphere. 2021;280:130747. 3. Mahajan PG, et al. Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics, chemoinformatics and computational approaches. Mol Divers. 2020 Nov;24(4):1185-1203. |