| Description | 2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechanism of 2'-O-Methyl-5-iodouridine is dependent on the inhibition of DNA synthesis and induction of apoptosis. |
| Synonyms | 5-Iodo-2'-O-methyluridine |
| molecular weight | 384.12 |
| Molecular formula | C10H13IN2O6 |
| CAS | 34218-84-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (143.18 mM) |
| References | 1. Gophane DB, et al. A semi-rigid isoindoline-derived nitroxide spin label for RNA. Org Biomol Chem. 2018;16(5):816-824. 2. Robak T, et al. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-3388. |