| Description | 2-MT 63 is a novel TIE-2 kinase inhibitor that demonstrates unique and improved kinase selectivity compared to other inhibitors known to interact with TIE-2. 2-MT 63 has a good kinase selectivity profile in enzyme assays with >30-fold selectivity (typically much greater) against the tested kinases. Importantly, the profile includes selectivity against other targets of relevance for angiogenesis (KDR, PDGFR, EPHB4). |
| molecular weight | 598.59 |
| Molecular formula | C29H30F4N8O2 |
| CAS | 870225-11-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |