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2-Di-1-ASP

CAS No.: 2156-29-8

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double
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Description 2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.
In vitro 2-Di-1-ASP在G4结构存在下显著增强荧光(高达300倍),并且相对于双链DNA具有良好的选择性。2-Di-1-ASP对平行G4-DNA形式(c-kit2, c-myc, c-kit87up)表现出荧光度选择性。
molecular weight 366.24
Molecular formula C16H19IN2
CAS 2156-29-8
Storage keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility DMSO: 20 mg/mL (54.61 mM), Sonication is recommended.
References 1. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.