| Description | (2-Chloropyridin-4-yl)methanamine hydrochloride is a selective LOXL2 inhibitor(IC50 : 126 nM). |
| In vitro | (2-Chloropyridin-4-yl)MethanaMine Hydrochloride (hLOXL2 IC50 = 126 nM) 被证明对LOXL2具有选择性，相较于LOX和其他三种胺氧化酶 (MAO-A, MAO-B, 与SSAO) 更为特异。 |
| Target activity | LOXL2:126 nM |
| molecular weight | 179.05 |
| Molecular formula | C6H8Cl2N2 |
| CAS | 916210-98-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (335.1 mM), Sonication is recommended. |
| References | 1. Hutchinson J H , Rowbottom M W , Lonergan D , et al. Small Molecule Lysyl Oxidase-like 2 (LOXL2) Inhibitors: The Identification of an Inhibitor Selective for LOXL2 over LOX[J]. ACS Medicinal Chemistry Letters, 2017, 8(4):423-427. |