| Description | 2,5-Dihydroxybiphenyl (TFIIH Modulator12), a small molecule destabilization inducer, induces the dimerization of trichothiodystrophy group A protein to modulate TFIIH transcriptional activity. |
| Synonyms | TFIIH Modulator 12, 2,5-二羟基联苯, TFIIH Modulator12 |
| molecular weight | 186.21 |
| Molecular formula | C12H10O2 |
| CAS | 1079-21-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 1.86 mg/mL (10 mM) |
| References | 1. Nakata Y, Nishi K, Nishimoto S, Sugahara T. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway. J Toxicol Sci. 2013;38(3):325-35. PubMed PMID: 23665931. |