| Description | 2,2′-Dipyridyl disulfide (Aldrithiol 2) is a useful reagent for the determination of sulfhydryl groups. It acts as a peptide coupling reagent and as an oxidizing agent. 2,2′-Dipyridyl disulfide (Aldrithiol 2) is also used for the activation of glycosides. |
| Synonyms | 2,2'-Dipyridyl disulfide, OPSS, 2,2'-二硫二吡啶, Aldrithiol 2, Orthopyridyl disulfide |
| molecular weight | 220.31 |
| Molecular formula | C10H8N2S2 |
| CAS | 2127-03-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (249.66 mM) |
| References | 1. Watanabe D, Kanzaki K, Kuratani M,et al. Contribution of impaired myofibril and ryanodine receptor function to prolonged low-frequency force depression after in situ stimulation in rat skeletal muscle. J Muscle Res Cell Motil. 2015 Jun;36(3):275-86. 2. Miller E, Spadaccia M, Sabado R, et al. Autologous aldrithiol-2-inactivated HIV-1 combined with polyinosinic-polycytidylic acid-poly-L-lysine carboxymethylcellulose as a vaccine platform for therapeutic dendritic cell immunotherapy. Vaccine. 2015 Jan 3;33(2):388-95. doi: 10.1016/j.vaccine.2014.10.054. Epub 2014 Nov 15. 3. Kanishchev OS, Dolbier WR Jr. Synthesis and characterization of 2-pyridylsulfur pentafluorides. Angew Chem Int Ed Engl. 2015 Jan 2;54(1):280-4. doi: 10.1002/anie.201409990. Epub 2014 Nov 6. 4. Basak D, Kumar R, Ghosh S. Telechelic Poly(disulfide)s and Related Block Copolymer. Macromol Rapid Commun. 2014 Aug;35(15):1340-4. |