| Description | Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive. |
| molecular weight | 320.473 |
| Molecular formula | C20H32O3 |
| CAS | 128914-47-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | PBS (pH 7.2): 0.8 mg/mL Ethanol: Miscible DMSO: Miscible 0.1 m Na2CO3: 2 mg/mL DMF: Miscible |