| Description | 10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2]. |
| In vitro | It is found that 10-DEBC inhibits the growth of Mtb in whole-cell assay with an IC 50 of 12.8 μM, while inhibiting replication of Mtb inside iMACs with an IC 50 of 1.5 μM, without host cell toxicity even at the highest concentration of 25 μM [2]. |
| molecular weight | 381.34 |
| Molecular formula | C20H26Cl2N2O |
| CAS | 925681-41-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |