1-Palmitoyl-2-hydroxy-sn-glycero-3-PE Bioactivity,Chemical Properties,Storage & Solubility Information Pathways-PeptideDB

Description	1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE has been used as an internal standard for the quantification of saturated lysophosphoethanolamines. [4]
Synonyms	1-Palmitoyl-2-hydroxy-sn-glycero-3-PE, 1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine
molecular weight	453.55
Molecular formula	C21H44NO7P
CAS	53862-35-4
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility	Chloroform: Soluble DMF: Soluble DMSO: Soluble
References	1. Nieman, D.C., Shanely, R.A., Gillitt, N.D., et al. Serum metabolic signatures induced by a three-day intensified exercise period persist after 14 h of recovery in runners. J. Proteome Res. 12(10), 4577-4584 (2013). 2. Achterberg, V., and Gercken, G. Cytotoxicity of ester and ether lysophospholipids on Leishmania donovani promastigotes. Mol. Biochem. Parasitol. 23(2), 117-122 (1987). 3. Li, S., Liu, H., Jin, Y., et al. Metabolomics study of alcohol-induced liver injury and hepatocellular carcinoma xenografts in mice. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 879(24), 2369-2375 (2011). 4. Avadhani, M., Geyer, R., White, D.C., et al. Lysophosphatidylethanolamine is a substrate for the short-chain alcohol dehydrogenase SocA from Myxococcus xanthus. J. Bacteriol. 188(24), 8543-8550 (2006).

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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE

CAS No.: 53862-35-4