| Description | 1-beta-D-Arabinofuranosyluracil (Uracil 1-β-D-arabinofuranoside) isolated from the Caribbean sponge Tectitethya crypta, is a methoxyadenosine derivative. 1-beta-D-Arabinofuranosyluracil has anti-inflammatory activity, analgesic and vasodilation properties. |
| In vivo | 1-beta-D-Arabinofuranosyluracil (ara-U)能在17 μm浓度下减少L5178Y小鼠淋巴瘤细胞的增殖，在剂量反应实验中，这一浓度能诱导50%的细胞增殖抑制[1]。 |
| Synonyms | 阿糖尿苷, 1-β-D-阿糖尿苷, Uracil 1-β-D-arabinofuranoside |
| molecular weight | 244.2 |
| Molecular formula | C9H12N2O6 |
| CAS | 3083-77-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 55 mg/mL (225.23 mM) |
| References | 1. W E Müller, Zahn R K . Metabolism of 1-beta-D-arabinofuranosyluracil in mouse L5178Y cells.[J]. Cancer Research, 1979, 39(3):1102-1107. 2. Bertin M J , Schwartz S L , Lee J , et al. Spongosine Production by a Vibrio harveyi Strain Associated with the Sponge Tectitethya crypta[J]. Journal of Natural Products, 2015, 78(3):493-499. |