| Description | 1. Yunaconitine (Guayewuanine B) has anti-inflammatory and analgesic actions. 2. Yunaconitine was shown to have anti-thermic effect in pyrexial rats when administered orally at a dose of 5 μg/kg. 3. Yunaconitine shows positive effect in the granuloma inhibition test when it was subcutaneously injected, 1 μg/kg for 6 d, or added directly to the cotton-pellet. 4. Yunaconitine inhibited the increased vascular permeability caused byacetic acid and histamine, the leucocyte migratory response induced by injection of 1 % carrageenin .1 ml in rat's thoracic cavity. |
| Synonyms | Guayewuanine B, 滇乌头碱 |
| molecular weight | 659.76 |
| Molecular formula | C35H49NO11 |
| CAS | 70578-24-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 9 mg/mL (13.64 mM) |
| References | 1. Zhi-Gong L , Wen C , Xi-Can T . Anti-inflammatory and analgesic actions of yunaconitine[J]. Chinese Journal of Pharmacology & Toxicology, 1987. |