| Description | Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals. |
| In vitro | Reinvestigation of Strychnos icaja Baillon resulted in the isolation of Vomicine, isostrychnine and of three new sungucine derivatives, named isosungucine (8), 18-hydroxy-sungucine (9) and 18-hydroxy-isosungucine (10). They were identified by detailed spectroscopic methods. The complete 1H- and 13C-NMR study of sungucine was also realized. Some of these compounds were highly active against Plasmodium falciparum in vitro and more particularly against the chloroquine-resistant strain[1] |
| Synonyms | 番木虌次碱, 番木鳖次碱 |
| molecular weight | 380.44 |
| Molecular formula | C22H24N2O4 |
| CAS | 125-15-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (131.43 mM) |
| References | 1. New antimalarial and cytotoxic sungucine derivatives from Strychnos icaja roots.Planta Med. 2000 Apr;66(3):262-9. |