| Description | Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without any cytotoxic effects on melan-a cells. It may have potential as a new skin whitening compound. |
| In vitro | 化合物的化学结构是通过光谱学方法确定的，包括快速原子轰击质谱(FAB-MS)、一维核磁共振(NMR)、二维核磁共振(2D-NMR)和红外光谱(IR)。化合物1、2和3在80 μM浓度下的黑色素生成抑制活性分别为23.9%、27.8%和35.2%。同样，这三种化合物在斑马鱼模型上显示出对体色素的抑制作用，斑马鱼模型通常用于生物医学或美容研究。 |
| Synonyms | 越南参皂苷R4 |
| molecular weight | 963.15 |
| Molecular formula | C48H82O19 |
| CAS | 156009-80-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/ml (62.29 mM) |
| References | 1. The potential of minor ginsenosides isolated from the leaves of Panax ginseng as inhibitors of melanogenesis.Int J Mol Sci. 2015 Jan 13;16(1):1677-90. |