| Description | Veratraldehyde (3,4-Dimethoxybenzaldehyde) has antifungal activity .It is found in Cymbopogon javanensis. |
| In vitro | Veratraldehyde与OG的组合克服了A. fumigatus mitogen-activated protein kinase (MAPK) 突变体对Kre-Me的耐药性，展现出更高的抗真菌活性 [1]。 |
| Cell experiments | The minimum inhibitory concentrations (MICs) of OG were 0.3-0.5 mM, while that of Veratraldehyde were 3.0-5.0 mM in agar plate-bioassays.?OG or Veratraldehyde in concert with the fungicide kresoxim methyl (Kre-Me;?strobilurin) greatly enhanced sensitivity of Aspergillus strains to Kre-Me.?The combination with OG also overcame the tolerance of A. fumigatus mitogen-activated protein kinase (MAPK) mutants to Kre-Me[2] |
| Synonyms | 3,4-Dimethoxybenzaldehyde, 藜芦醛 |
| molecular weight | 166.17 |
| Molecular formula | C9H10O3 |
| CAS | 120-14-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 27.5 mg/mL (165.49 mM) |
| References | 1. Kim J H , Mahoney N , Chan K L , et al. Use of benzo analogs to enhance antimycotic activity of kresoxim methyl for control of aflatoxigenic fungal pathogens[J]. Frontiers in Microbiology, 2014, 5. 2. B.S. Shylesha,T.V. Venkatesha,and B. M. Praveen. Veratraldehyde as Corrosion Inhibitor for Zinc in Different Acid Medium[J].Der Pharma Chemica, 2010, 2(6): 295-301 |