| Description | Valencene (NSC-148969) is a sesquiterpenoid isolated from Cyperus rotundus and is an aroma component of citrus fruits and citrus-derived odors.ValenceneValencene has anti-allergic, anti-inflammatory, anti-melanogenic, and antioxidant activities. Valencene inhibits the overexpression of Th2 chemokines and pro-inflammatory chemokines by blocking the NF-κB pathway. |
| Synonyms | NSC 148969, NSC-148969, NSC148969 |
| molecular weight | 204.35 |
| Molecular formula | C15H24 |
| CAS | 4630-07-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45.0 mg/mL (220.2 mM), Sonication is recommended. |
| References | 1. Frohwitter J, et al. Production of the sesquiterpene (+)-valencene by metabolically engineered Corynebacterium glutamicum. J Biotechnol. 2014;191:205-213. 2. Yu Q, et al. Deficiency of valencene in mandarin hybrids is associated with a deletion in the promoter region of the valencene synthase gene. BMC Plant Biol. 2019;19(1):101. 3. Scholtmeijer K, et al. Production of (+)-valencene in the mushroom-forming fungus S. commune. Appl Microbiol Biotechnol. 2014;98(11):5059-5068. 4. Beekwilder J, et al. Valencene synthase from the heartwood of Nootka cypress (Callitropsis nootkatensis) for biotechnological production of valencene. Plant Biotechnol J. 2014;12(2):174-182. |