| Description | Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO production inhibitory activities. Acetylursolic acid has inhibition against both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. |
| Synonyms | 熊果酸乙酸酯, Acetylursolic acid, 3-Acetylursolic Acid |
| molecular weight | 498.74 |
| Molecular formula | C32H50O4 |
| CAS | 7372-30-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 12 mg/mL (24.06 mM) Chloroform, Dichloromethane, Ethyl Acetate: Soluble |
| References | 1. Tu, H., Huang, A., Wei, B., Gan, K., Hour, T., & Yang, S. et al. (2009). Ursolic acid derivatives induce cell cycle arrest and apoptosis in NTUB1 cells associated with reactive oxygen species. Bioorganic & Medicinal Chemistry, 17(20), 7265-7274. doi: 10.1016/j.bmc.2009.08.046 2. Leal, A., Wang, R., Salvador, J., & Jing, Y. (2012). Synthesis of novel ursolic acid heterocyclic derivatives with improved abilities of antiproliferation and induction of p53, p21waf1 and NOXA in pancreatic cancer cells. Bioorganic & Medicinal Chemistry, 20(19), 5774-5786. doi: 10.1016/j.bmc.2012.08.010 |