| Description | trans-Vaccenic acid is a precursor substance that synthesizes saturated fatty acids in the rumen and conjugated linoleic acid at the tissue level. trans-Vaccenic acid inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells through the mitochondria-mediated apoptotic pathway. |
| Synonyms | TVA, （11E)-octadec-11-enoic acid, 11E)-octadec-11-enoic acid |
| molecular weight | 282.46 |
| Molecular formula | C18H34O2 |
| CAS | 693-72-1 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 98 mg/mL (346.95 mM), Sonication is recommended. |
| References | 1. Li D, et al. Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro. BMC Res Notes. 2012 Feb 15;5:97. 2. Fan H, Xia S, Xiang J, et al. Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity. Nature. Published online November 22, 2023. doi:10.1038/s41586-023-06749-3 |