| Description | Tokinolide B may have sedative and spasmolytic properties. |
| In vitro | The chemical constituents of the organic extracts from the rhizomes of Ligusticum porteri were isolated, characterised and identified as Z-ligustilide, Z-butylidenephthalide, diligustilide, Tokinolide B, riligustilide, senkyunolides F and I, ferulic acid, among other known compounds. The preparation of 4,5-dehydroTokinolide B from Tokinolide B is reported, and its structure confirmed by X-ray analysis. The sedative and spasmolytic activities of some of these natural products and derivatives were evaluated by applying them to in vivo and in vitro models. |
| molecular weight | 380.484 |
| Molecular formula | C24H28O4 |
| CAS | 112966-16-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Phthalides and other constituents from Ligusticum porteri; sedative and spasmolytic activities of some natural products and derivatives.Nat Prod Res. 2011 Aug;25(13):1234-42. |