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Tingenone

CAS No.: 50802-21-6

Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation.
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Description Tingenone is a pentacyclic triterpene. It induces peripheral antinociception due to opioidergic activation.
Synonyms Maytenin, Maitenin, Tingenin A, Tingenon
molecular weight 420.593
Molecular formula C28H36O3
CAS 50802-21-6
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Veloso Cde C, Rodrigues VG, Ferreira RC, Duarte LP, Klein A, Duarte ID, Romero TR, Perez Ade C. Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to opioidergic activation. Planta Med. 2014 Nov;80(17):1615-21. doi: 10.1055/s-0034-1383147. Epub 2014 Oct 22. PubMed PMID: 25338214. 2. de Carvalho Veloso C, Rodrigues VG, Ferreira RC, Duarte LP, Klein A, Duarte ID, Romero TR, de Castro Perez A. Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K(+) channels pathway activation in mice. Eur J Pharmacol. 2015 May 15;755:1-5. doi: 10.1016/j.ejphar.2015.02.038. Epub 2015 Mar 5. PubMed PMID: 25748602. 3. Setzer WN, Setzer MC, Hopper AL, Moriarity DM, Lehrman GK, Niekamp KL, Morcomb SM, Bates RB, McClure KJ, Stessman CC, Haber WA. The cytotoxic activity of a Salacia liana species from Monteverde, Costa Rica, is due to a high concentration of tingenone. Planta Med. 1998 Aug;64(6):583. PubMed PMID: 9741306. 4. Goijman SG, Turrens JF, Marini-Bettolo GB, Stoppani AO. Effect of tingenone, a quinonoid triterpene, on growth and macromolecule biosynthesis in Trypanosoma cruzi. Experientia. 1985 May 15;41(5):646-8. PubMed PMID: 3888660.