Description | Tigloylgomisin P shows moderate to marginal cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines. |
In vitro | Bioactivity-directed fractionation of an ethanolic extract of the fruits of Schisandra rubriflora led to the isolation and identification of dibenzocyclooctadiene lignans including the new lignans rubrisandrins A (1a + 1b) and B (2) and the known lignans gomisin J (3), (+/-)-gomisin M1 (4), (+)-gomisin M2 (5), schisanhenol (6), deoxyschisandrin, schisantherin B, schisandrin, Tigloylgomisin P, gomisin O, angeloylgomisin P, and epigomisin O. Their structure and stereochemistry were determined by spectroscopic methods, including 2D-NMR techniques. |
Synonyms | 巴豆酰戈米辛 P, 巴豆酰戈米辛P |
molecular weight | 514.56 |
Molecular formula | C28H34O9 |
CAS | 69176-51-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
References | 1. Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora.J Nat Prod. 2006 Dec;69(12):1697-701. |