| Description | Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity. |
| Synonyms | Senegenin, Senegin, 远志皂苷元 |
| molecular weight | 537.13 |
| Molecular formula | C30H45ClO6 |
| CAS | 2469-34-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 91 mg/mL(169.4 mM) Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble |
| References | 1. Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDIα.Mol Neurobiol. 2015 Dec;52(3):1561-71. 2. Yu L , Sun L , Chen S .Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.Exp Ther Med. 2014 Apr;7(4):821-826. 3. Xie W, Yang Y, Gu X, Zheng Y,et al.Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats.PLoS One. 2012;7(9):e45575. |