| Description | Teicoplanin (MDL-507) is a semisynthetic glycopeptide antibiotic, used to treat Gram-positive bacteria. |
| In vivo | 在中性粒细胞缺乏的小鼠中，Teicoplanin治疗能提高存活率，而G-CSF治疗与其他组相比并无此效果。Teicoplanin与G-CSF联合治疗与第二、三、四组相比能够提高存活率。[5] |
| Synonyms | Antibiotic MDL-507, MDL-507, 替考拉宁, Teichomycin |
| molecular weight | 1725.42 |
| Molecular formula | C78H79Cl2N9O33 |
| CAS | 61036-62-2 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 100 mg/mL, Sonication is recommended. DMSO: 100 mg/mL, Sonication is recommended. |
| References | 1. Samonis G, et al. Med Mycol,2006, 44(2), 193-196. 2. Filice G, et al. Microbiologica, 1990, 13(3), 231-237. 3. Cheng JK, et al. J Pharmacol Sci, 2006, 100(5), 471-486. 4. Chmara H, et al. J Gen Microbiol, 1991, 137(4), 913-919. 5. Oz N, et al. Int J Surg Investig,2001, 2(5), 347-352. 6. Davis T D, Kunakom S, Burkart M D, et al. Preparation, Assay, and Application of Chlorinase SalL for the Chemoenzymatic Synthesis of S-Adenosyl-L-Methionine and Analogs[M]//Methods in enzymology. Academic Press. 2018;604:367-388. |