| Description | Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR). |
| In vitro | 肝脏将Obeticholic acid和taurine结合形成taurine-obeticholic acid，然后该化合物被分泌至胆汁中。伊雷和结肠内的微生物能够分解taurine-obeticholic acid，并将其还原成母化合物，随后该化合物可以被重新吸收或通过粪便排出。 |
| molecular weight | 527.76 |
| Molecular formula | C28H49NO6S |
| CAS | 863239-61-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (94.74 mM) |
| References | 1. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6. |