| Description | Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals. |
| In vitro | A herbicidal compound was isolated from extracts ofMatthiola incana and identified as Sulforaphene (4-methylsulfinyl-3-butenyl isothiocyanate). CONCLUSIONS: The ED50 of this compound against velvetleaf seedlings was approximately 2×10(-4) M. Glucoraphenin, the glucosinolate that is the natural precursor of Sulforaphene, was less phytotoxic, with an ED50 of near 6×10(-3)M. |
| Synonyms | 油菜 |
| molecular weight | 175.27 |
| Molecular formula | C6H9NOS2 |
| CAS | 592-95-0 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (570.55 mM), Sonication is recommended. |
| References | 1. Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84. 2. Sulforaphene inhibits triple negative breast cancer through activating tumor suppressor Egr1. Breast Cancer Res Treat. 2016 Jul;158(2):277-86. 3. Characterization of Anti-proliferative and Antibacterial Properties of Sulforaphene Obtained from Radish Seeds, Ashs Conference. 2013. |