| Description | Spaglumic acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in the brain. |
| In vitro | Spaglumic Acid在Ca2+依赖的过程中因去极化而释放，是mGluR3受体的激动剂和NMDA受体的拮抗剂。Spaglumic Acid主要通过表达在星形胶质细胞外表面的谷氨酸羧肽酶II被分解为N-乙酰天门冬氨酸和谷氨酸[1]。 |
| Synonyms | 异冬谷酸, N-Acetylaspartylglutamic acid, NAAG |
| molecular weight | 304.25 |
| Molecular formula | C11H16N2O8 |
| CAS | 3106-85-2 |
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 29 mg/mL(95.31 mM) |
| References | 1. Coyle JT. The nagging question of the function of N-acetylaspartylglutamate. Neurobiol Dis. 1997;4(3-4):231-8. |