| Description | Sodium Houttuyfonate (Houttuynin sodium bisulfite), the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis. |
| In vitro | 使用 Sodium Houttuyfonate 处理可以提高巨噬细胞中c-Fos蛋白的表达水平，同时对细胞外信号调节激酶1/2（ERK1/2）的磷酸化水平没有影响[1]。 |
| In vivo | Sodium Houttuyfonate已被证明能通过降低尿蛋白、改善形态特征和抑制单核细胞趋化蛋白1（MCP-1）[1]的方式，保护BALB/C小鼠免受阳离子化牛血清白蛋白（C-BSA）诱导的肾小球肾炎。 |
| Synonyms | Houttuynin sodium bisulfite, 新鱼腥草素钠 |
| molecular weight | 302.36 |
| Molecular formula | C12H23NaO5S |
| CAS | 83766-73-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 20 mg/mL (66.15 mM), Sonication is recommended. H2O: 3.33 mg/mL (11.02 mM), Sonication is recommended. |
| References | 1. Chen J, Wang W, Shi C, Fang J. A comparative study of sodium houttuyfonate and 2-undecanone for their in vitro and in vivo anti-inflammatory activities and stabilities. Int J Mol Sci. 2014;15(12):22978-22994. Published 2014 Dec 11. doi:10.3390/ijms151222978 |