| Description | Sikokianin A shows in vitro antiviral activity against HBsAg secretion. |
| In vitro | Two new C-3/C-3'' biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), Sikokianin A (6), and chamaejasmenin C (7). METHODS AND RESULTS:Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12 microg/ml, respectively. |
| molecular weight | 556.523 |
| Molecular formula | C31H24O10 |
| CAS | 106293-99-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Antimitotic and antifungal C-3/C-3''-biflavanones from Stellera chamaejasme. Chem Pharm Bull (Tokyo). 2005 Jul;53(7):776-9. |