| Description | Sarpagine is an alkaloid with the antihypertonic effect. |
| Synonyms | Raupin |
| molecular weight | 310.39 |
| Molecular formula | C19H22N2O2 |
| CAS | 482-68-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. Namjoshi OA, Cook JM. Sarpagine and Related Alkaloids. Alkaloids Chem Biol. 2016;76:63-169. doi: 10.1016/bs.alkal.2015.08.002. Epub 2015 Oct 9. Review. PubMed PMID: 26827883; PubMed Central PMCID: PMC4864735. 2. Lim SH, Low YY, Sinniah SK, Yong KT, Sim KS, Kam TS. Macroline, akuammiline, sarpagine, and ajmaline alkaloids from Alstonia macrophylla. Phytochemistry. 2014 Feb;98:204-15. doi: 10.1016/j.phytochem.2013.11.014. Epub 2013 Dec 13. PubMed PMID: 24342109. 3. Tan SJ, Lim JL, Low YY, Sim KS, Lim SH, Kam TS. Oxidized derivatives of macroline, sarpagine, and pleiocarpamine alkaloids from Alstonia angustifolia. J Nat Prod. 2014 Sep 26;77(9):2068-80. doi: 10.1021/np500439u. Epub 2014 Sep 11. PubMed PMID: 25211145. 4. Krüger S, Gaich T. Enantioselective, protecting-group-free total synthesis of sarpagine alkaloids--a generalized approach. Angew Chem Int Ed Engl. 2015 Jan 2;54(1):315-7. doi: 10.1002/anie.201407280. Epub 2014 Oct 24. PubMed PMID: 25346454. |