| Description | Sapienic acid is a fatty acid commonly found on the skin and in the mucosa. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively. |
| In vitro | Sapienic acid (minimum bactericidal concentrations (MBCs) range, 31.3 to 375.0 μg/mL) is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum but not active against Escherichia coli, Staphylococcus aureus, S. marcescens, P. aeruginosa, Corynebacterium bovis, Corynebacterium striatum, and Corynebacterium jeikeium (MBC > 500 μg/mL) [1]. |
| Target activity | Streptococcus mitis:93.8 μg/ml, MBC: 31.3 μg/ml, Fusobacterium nucleatum:, Streptococcus sanguinis:375.0 μg/ml |
| molecular weight | 254.41 |
| Molecular formula | C16H30O2 |
| CAS | 17004-51-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Fischer CL, et al. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrob Agents Chemother. 2012 Mar;56(3):1157-61. |