| Description | Sanggenon D (Sanggenone D), a small molecule compound from Morus alba Bark, is a GABA(A) receptor modulator with antioxidant and antibacterial activity, inhibits breast cancer cell proliferation, and inhibits the growth of Staphylococcus aureus by modulating the fatty acid biosynthesis system. |
| In vitro | 以酪氨酸为底物，在30和100 μM条件下，测定了sanggenon D对酪氨酸酶的抑制活性，其IC50值是7.3μM。[3] |
| Synonyms | Sanggenone D |
| molecular weight | 708.71 |
| Molecular formula | C40H36O12 |
| CAS | 81422-93-7 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (112.88 mM), Sonication is recommended. |
| References | 1. Judith M Rollinger,et al.Venturia inaequalis-inhibiting Diels-Alder adducts from Morus root bark. J Agric Food Chem. 2006 Nov 1;54(22):8432-6. 2. Y S Chi,et al.Effects of naturally occurring prenylated flavonoids on enzymes metabolizing arachidonic acid: cyclooxygenases and lipoxygenases. Biochem Pharmacol. 2001 Nov 1;62(9):1185-91. 3. Lee NK, et al. Prenylated flavonoids as tyrosinase inhibitors. Arch Pharm Res. 2004 Nov;27(11):1132-5. |