| Description | Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. |
| Synonyms | 柴胡皂苷B1, 柴胡皂苷 B1 |
| molecular weight | 780.98 |
| Molecular formula | C42H68O13 |
| CAS | 58558-08-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (64.02 mM) |
| References | 1. Kyo R., et al. Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells. Biol Pharm Bull 22:1385-7 (1999). 2. Kida H., et al. Metabolism and pharmacokinetics of orally administered saikosaponin b1 in conventional, germ-free and Eubacterium sp. A-44-infected gnotobiote rats. Biol Pharm Bull 21:588-93 (1998). 3. Nishiyama T., et al. A distinct characteristic of the quiescent state of human dermal fibroblasts in contracted collagen gel as revealed by no response to epidermal growth factor alone, but a positive growth response to a combination of the growth factor and saikosaponin b1. Matrix 10:412-9 (1990). |