| Description | Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2. |
| Target activity | COX-2:9 μM (IC50), COX-1:5 μM (IC50) |
| molecular weight | 440.7 |
| Molecular formula | C30H48O2 |
| CAS | 6812-81-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (136.14 mM) |
| References | 1. Cao H,et al. Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation. Pharmacol Res. 2010 Jun;61(6):519-24. 2. Chen QL,et al. [Studies on the chemical constituents in root of Gentiana macrophylla from Shaanxi]. Zhongguo Zhong Yao Za Zhi. 2005 Oct;30(19):1519-22. |