| Description | Regaloside A is a phenylpropane derived from lily of the valley that shows DPPH free radical scavenging activity at 160 ppm.Regaloside A has anti-inflammatory activity and antidepressant activity. |
| In vitro | Regaloside A (50 μg/mL; 预处理2小时) 后接受LPS处理 (1 μg/mL; 预处理15分钟) 的Raw 264.7细胞中，iNOS表达被抑制至70.3，COX-2表达减少至131.6。此外，Regaloside A将p-p65/p-65比率降低至40.7。[1] 在HASMCs中，先行用Regaloside A (50 μg/mL)处理2小时后，再暴露于TNF-α (10 ng/mL) 12小时，可见VCAM-1表达降至48.6。[1] |
| molecular weight | 400.38 |
| Molecular formula | C18H24O10 |
| CAS | 114420-66-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (112.39 mM) |
| References | 1. Thi N N, et al. Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities. Applied Biological Chemistry. 2017; 60: 527-533. 2. Qin Y, et al. Integrative analysis of metabolome and transcriptome provide new insights into the bitter components of Lilium lancifolium and Lilium brownii. J Pharm Biomed Anal. 2022;215:114778. |