| Description | Protectin D1 (Neuroprotectin D1) is a neuroprotectin produced by neuronal cells and is a potential cardioprotective agent.Protectin D1 attenuates myocardial ischemia/reperfusion injury and inhibits imiquimod-induced psoriasis-like skin inflammation by modulating the PI3K/AKT signaling pathway. |
| Synonyms | Neuroprotectin D1, NPD1 |
| molecular weight | 360.49 |
| Molecular formula | C22H32O4 |
| CAS | 660430-03-5 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL PBS (pH 7.2): 0.1 mg/mL Ethanol: 50 mg/mL DMF: 50 mg/mL |
| References | 1. Zhang P,et al. Protectin D1 Alleviates Myocardial Ischemia/Reperfusion Injury by Regulating PI3K/AKT Signaling Pathway. J Cardiovasc Transl Res. 2023 Aug 14. 2. Park KD,et al. Protectin D1 reduces imiquimod-induced psoriasiform skin inflammation. Int Immunopharmacol. 2021 Sep;98:107883. 3. Liu H,et al. Protectin D1 inhibits TLR4 signaling pathway to alleviate non-alcoholic steatohepatitis via upregulating IRAK-M. Free Radic Biol Med. 2024 Jan;210:42-53. |