| Description | Prenyletin is a natural product found in the multilobed bimodal, multihorned pterosaurs. |
| In vitro | 来自巴西南部、传统上用于治疗动物真菌病的Pterocaulon alopecuroides、Pterocaulon balansae和Pterocaulon polystachyum (Asteraceae)提取出了香豆素化合物5-甲氧基-6,7-亚甲二氧基香豆素、7-(2',3'-环氧-3'-甲基丁氧基)-6-甲氧基香豆素、6,7-亚甲二氧基香豆素（ayapin），以及6-羟基-7-(3'-甲基丁-2'-烯氧基)-香豆素（prenyletin）与6-甲氧基-7-(3'-甲基丁-2'-烯氧基)-香豆素（prenyletin-甲基-醚）的混合物。在活性提取物的不同成分中，仅从Pterocaulon polystachyum分离的prenyletin和prenyletin-甲基醚混合物对Cryptococcus neoformans、Microsporum gypseum、Trichophyton rubrum和Trichophyton mentagrophytes显示活性。然而，它们的MIC值高于原始提取物的MIC值，这表明活性并非仅由一个化合物负责，而是该混合物在这些Pterocaulon种中检测到的活性负责。[1] |
| molecular weight | 246.26 |
| Molecular formula | C14H14O4 |
| CAS | 15870-91-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (203.04 mM) |
| References | 1. Stein AC, et al. Antifungal activity of some coumarins obtained from species of Pterocaulon (Asteraceae). J Ethnopharmacol. 2006;107(1):95-98. 2. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005;37(5):436-446. 3. Vera N, et al. New coumarins from Pterocaulon polystachyum. Planta Med. 2001;67(7):674-677. |