| Description | Prehispanolone is a platelet activating factor antagonist from Chinese medicinal herb Leonurus heterophyllus. |
| Synonyms | LC 5504, LC5504, LC-5504 |
| molecular weight | 318.457 |
| Molecular formula | C20H30O3 |
| CAS | 132922-55-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lee CM, Jiang LM, Shang HS, Hon PM, He Y, Wong HN. Prehispanolone, a novel platelet activating factor receptor antagonist from Leonurus heterophyllus. Br J Pharmacol. 1991 Jul;103(3):1719-24. PubMed PMID: 1657264; PubMed Central PMCID: PMC1907812. 2. Xu HM, Lee CM, Hon PM, Chang HM. [Proliferation of lymphocytes T and B by prehispanolone LC-5504 of Leonurus hereterophyllus Sweet]. Yao Xue Xue Bao. 1992;27(11):812-6. Chinese. PubMed PMID: 1300024. 3. Moon HI. Three diterpenes from Leonurus japonicus Houtt protect primary cultured rat cortical cells from glutamate-induced toxicity. Phytother Res. 2010 Aug;24(8):1256-9. doi: 10.1002/ptr.3144. PubMed PMID: 20658574. |