| Description | Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity. |
| In vitro | Pimpinellin had potent cytotoxic activities against the three cell lines, with the IC50 values of 14.4?±?0.3?μM, 20.4?±?0.5?μM, and 29.2?±?0.6?μM, respectively. The mechanism of the antitumor action indicated that pimpinellin inhibited the growth of MGC-803 cells via the induction of tumor cell apoptosis, with apoptosis ratio of 27.44% after 72?h of treatment at 20?μM. |
| molecular weight | 246.22 |
| Molecular formula | C13H10O5 |
| CAS | 131-12-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 49 mg/mL (199.0 mM) |
| References | 1. Yang S , Liu M , Liang N , et al. Discovery and antitumor activities of constituents fromCyrtomium fortumei(J.) Smith rhizomes[J]. Chemistry Central Journal, 2013, 7(1):24. |