| Description | Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities. Physcion 8-O-β-D-glucopyranoside can be used in studies about common malignancy cancer. |
| In vitro | Physcion 8-O-β-D-glucopyranoside 通过TNF-R1[1]途径,抑制TNF-α±引起的L929细胞的细胞毒性和凋亡。 |
| Synonyms | 大黄素甲醚-8-O-Β-D-葡萄糖苷, Physcion 8-O-beta-D-monoglucoside |
| molecular weight | 446.4 |
| Molecular formula | C22H22O10 |
| CAS | 23451-01-6 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mg/mL (22.4 mM) |
| References | 1. Cao Y, et al. Identification of a ligand for tumor necrosis factor receptor from Chinese herbs by combination of surface plasmon resonance biosensor and UPLC-MS. Anal Bioanal Chem. 2016 Jul;408(19):5359-67. 2. C-L Xue, et al. Physcion 8-O-β-glucopyranoside exhibits anti-growth and anti-metastatic activities in ovarian cancer by downregulating miR-25.Eur Rev Med Pharmacol Sci. 2019 Jun;23(12):5101-5112. |