| Description | PALATINOSE (TNP-470) is a natural occurring disaccharide composed of alpha-1,6-linked glucose and fructose。 PALATINOSE has a beneficial effect on liver metabolic functions and might therefore be a good substitute for sucrose as a sweetener. |
| In vivo | 与摄取蔗糖饮食的小鼠相比，摄取palatinose diet 饮食的小鼠表现出更低的血清葡萄糖、胰岛素和总胆固醇水平，同时多个与脂肪合成相关的基因和蛋白的表达也有所下降。Palatinose diet 饲养小鼠的肝细胞组织学分析显示正常形态。综上所述，palatinose diet 的摄入降低了肝脏脂肪合成，并且相较于蔗糖，更有助于维持更佳的胆固醇平衡。 |
| Synonyms | TNP-470, 帕拉金糖水合物, Isomaltulose |
| molecular weight | 342.3 |
| Molecular formula | C12H22O11 |
| CAS | 13718-94-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/ml (175.28 mM) |
| References | 1. Hwang D, Park HR, Lee SJ, Kim HW, Kim JH, Shin KS. Oral administration of palatinose vs sucrose improves hyperglycemia in normal C57BL/6J mice. Nutr Res. 2018 Nov;59:44-52. 2. Isomaltulose (Palatinose): a review of biological and toxicological studies |