| Description | Oroxylin A-7-O-glucuronide (Oroxylin A Glucoronide) and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the "stem" region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively. |
| Synonyms | Oroxylin A Glucoronide, 千层纸素A-7-0-Β-D-葡萄糖醛酸苷, Oroxyloside, Oroxylin A 7-O-beta-D-glucuronide |
| molecular weight | 460.39 |
| Molecular formula | C22H20O11 |
| CAS | 36948-76-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (130.32 mM) Ethanol: Soluble Pyridine, Methanol, etc.: Soluble |
| References | 1. Zhou XQ., et al. Flavonoids from Scutellaria baicalensis and their bioactivities. 2. Li C., et al. Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix Scutellariae. J Pharm Biomed Anal. 2009 Oct 15;50(3):298-306. |