| Description | Oleoylcarnitine (Oleoyl-L-carnitine) inhibits adenine nucleotide translocase (AdNT) activity with an ic50 of 14 μM.Oleoylcarnitine is an important indicator of neurodegeneration. |
| In vitro | 在 Dih 10 细胞和 HCC 细胞中，Oleoylcarnitine（5、25、50 µM；24、48 小时）可以通过激活 STAT3，增强了 HCC 细胞的自我更新能力，促进了肝癌的发生[1]。 |
| Synonyms | Oleoyl-L-carnitine |
| molecular weight | 425.64 |
| Molecular formula | C25H47NO4 |
| CAS | 38677-66-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (187.95 mM), Sonication is recommended. |
| References | 1. Fujiwara N, et al. CPT2 downregulation adapts HCC to lipid-rich environment and promotes carcinogenesis via acylcarnitine accumulation in obesity. Gut. 2018 Aug;67(8):1493-1504. |