| Description | Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis. |
| Target activity | Aromatase:28.4 μM |
| molecular weight | 454.51 |
| Molecular formula | C26H30O7 |
| CAS | 751-03-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble DMSO: 82 mg/mL(180.4 mM) |
| References | 1. Murthy KN, et al.Toxicology. 2015 Mar 2;329:88-97. 2. Kim J, et al. Biochimie. 2014 Oct;105:36-44. 3. Vikram A, et al. Appl Environ Microbiol. 2012 Oct;78(19):72012-22. |