| Description | (+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity. |
| In vitro | (+)-Nortrachelogenin在体外对HIV-1表现出中等活性。它还能引起P. oryzae菌丝的形态变形，其最小形态变化浓度（MMDC）为31.3 microM[1]。 |
| In vivo | (+)-Nortrachelogenin 在中央神经系统上显示出作用，造成兔子出现抑郁症状[2]。 |
| Synonyms | Wikstromol, 荛花酚 |
| molecular weight | 374.38 |
| Molecular formula | C20H22O7 |
| CAS | 61521-74-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7. 2. Kato A, Hashimoto Y, Kidokoro M. (+)Nortrachelogenin, a new pharmacologically active lignan from Wikstroemia indica. Lloydia. 1979 Mar-Apr;42(2):159-62. |