| Description | N-Methyllaurotetanine is a natural product with good affinity for the 5-HT1A receptor. |
| Synonyms | NSC-247506, NSC247506, Rogersine, Lauroscholtzine, NSC 247506 |
| molecular weight | 341.4 |
| Molecular formula | C20H23NO4 |
| CAS | 2169-44-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: Soluble |
| References | 1. Madapa S, Harding WW. Semisynthetic Studies on and Biological Evaluation of N-Methyllaurotetanine Analogues as Ligands for 5-HT Receptors. J Nat Prod. 2015 Apr 24;78(4):722-9. doi: 10.1021/np500893h. Epub 2015 Feb 19. PubMed PMID: 25695425. 2. Nafiah MA, Mukhtar MR, Omar H, Ahmad K, Morita H, Litaudon M, Awang K, Hadi AH. N-cyanomethylnorboldine: a new aporphine isolated from Alseodaphne perakensis (Lauraceae). Molecules. 2011 Apr 20;16(4):3402-9. doi: 10.3390/molecules16043402. PubMed PMID: 21512448. 3. Cahlíková L, Hulová L, Hrabinová M, Chlebek J, Hošťálková A, Adamcová M, Šafratová M, Jun D, Opletal L, Ločárek M, Macáková K. Isoquinoline alkaloids as prolyl oligopeptidase inhibitors. Fitoterapia. 2015 Jun;103:192-6. doi: 10.1016/j.fitote.2015.04.004. Epub 2015 Apr 9. PubMed PMID: 25863351. 4. Qu YH, Jiang M, Wang LY, Li YC, Wang YN, Guo QL, Li YJ, Lin S. [Aporphine alkaloids from Litsea greenmaniana]. Zhongguo Zhong Yao Za Zhi. 2015 Jan;40(1):94-7. Chinese. PubMed PMID: 25993795. |