| Description | N-Feruloylserotonin ((E/Z)-Moschamine) is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations. |
| In vitro | N-Feruloylserotonin处理显著减轻了脂多糖(LPS)诱导的活性氧、一氧化氮和前列腺素E2在RAW 264.7巨噬细胞中的产生[1]。 |
| Synonyms | (E/Z)-Moschamine, Moschamine |
| molecular weight | 352.38 |
| Molecular formula | C20H20N2O4 |
| CAS | 68573-23-9 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (227.03 mM), Sonication is recommended. |
| References | 1. Park CH, et al. N-Feruloylserotonin inhibits lipopolysaccharide-induced inflammation via SIRT1-stimulated FOXO1 and NF-κB signaling pathways in RAW 264.7 cells. Cell Mol Biol (Noisy-le-grand). 2023 Nov 15;69(11):109-115. 2. Katsuda S,et al. Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin)ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. Hypertens Res. 2009 Nov;32(11):944-9. |